Short-term arsenic poisoning can cause unpleasant symptoms, but the outlook remains good overall. The most serious problems tend to occur from exposure to arsenic over long periods of time. This can happen at a daily job, or by eating or breathing contaminants on a regular basis.
The earlier you catch arsenic exposure, the better the outlook. You can also reduce your cancer risk when you catch it early.
Ground water continues to be the most common source of arsenic poisoning. One of the most effective preventive measures against arsenic poisoning is to make sure you drink clean, filtered water. You can also make sure that all foods are prepared in clean water. If you work in industries that use arsenic, take extra precautions.
Bring your own water from home, and wear a mask to reduce accidental arsenic inhalation. Hemlock is a poisonous plant that can kill you.
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Health Conditions Discover Plan Connect. Arsenic trioxide injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Arsenic Trioxide Injection pronounced as ar' se nik trye ox' ide. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow?
What side effects can this medication cause? Brand names. Talk to your doctor about the risks of taking arsenic trioxide. Other uses for this medicine. What special precautions should I follow? Before receiving arsenic trioxide injection, tell your doctor and pharmacist if you are allergic to arsenic trioxide, any other medications, or any of the ingredients in arsenic trioxide injection.
Ask your pharmacist for a list of the ingredients. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. If you are female, you will need to take a pregnancy test before starting treatment and use birth control to prevent pregnancy during your treatment and for at least 6 months after your final dose.
Breathing sawdust from wood treated with arsenic or breathing smoke from burning wood treated with arsenic is another way to be exposed to arsenic. Some areas of the world have high levels of arsenic in rock that can increase exposure to those living nearby.
Breathing high levels of inorganic arsenic can give you a sore throat or irritated lungs. Ingesting swallowing high levels of inorganic arsenic can result in death.
Lower levels of arsenic can cause nausea and vomiting, decreased red and white blood cells, abnormal heart rhythm, and numbness and tingling in the hands and feet. Organic arsenic compounds are less toxic than inorganic arsenic.
Exposure to high levels of organic arsenic may cause similar effects as inorganic arsenic. Arsenic-containing preparations have been in medical use for more than years. Arsenic-based therapy was used in the United States and Europe more than years ago to treat leukemia and infections, but modern chemotherapy and antibiotics replaced these treatments.
More recently, interest in arsenic-based therapy was revived by reports of the anti-leukemic activity of some traditional Chinese preparations. Chinese scientists subsequently found out that the active ingredient was arsenic trioxide. The mechanism of action of arsenic trioxide is not well understood. There is speculation that it causes death of leukemia cells via morphological changes and DNA fragmentation.
Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice. For information about the 4th Angel Mentoring Program visit www. Toggle navigation. Spanish About Chemocare. Arsenic Trioxide. What Arsenic Trioxide Is Used For: Acute promyelocytic leukemia APL Note: If a drug has been approved for one use, physicians sometimes elect to use this same drug for other problems if they believe it may be helpful.
This may be extended up to four hours if the patient has a vasomotor reaction lightheadedness, change in blood pressure. Side Effects of Arsenic Trioxide: Important things to remember about the side effects of Arsenic Trioxide: Most people do not experience all of the side effects listed. Arsenic Trioxide's side effects are often predictable in terms of their onset and duration. Arsenic Trioxide's side effects are almost always reversible and will go away after treatment is complete.
There are many options to help minimize or prevent side effects. There is no relationship between the presence or severity of side effects and the effectiveness of the medication. Your white and red blood cells and platelets may temporarily decrease. Blood count abnormalities high potassium level low calcium level Weight gain Vaginal bleeding see bleeding problems Dry skin see skin reactions A possible, but rare serious side effect that is preventable with proper monitoring and immediate treatment is APL differentiation syndrome.
This syndrome is a reaction between the drug and the leukemia. This syndrome produces fever, difficulty breathing, weight gain and lung and heart problems. It is generally treated with high-dose steroids. In most cases, treatment with arsenic trioxide will continue.
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