Studies have found grapefruit can help with weight loss, but weight loss on the grapefruit diet may be due to consuming fewer calories. Grapefruit juice and fresh grapefruit can be part of a balanced, healthy diet But grapefruit can also interfere with certain medications , including:.
Grapefruit juice tends to interfere with the action of these drugs because it contains a class of chemicals called furanocoumarins.
Studies show that furanocoumarins may increase the blood levels of over 85 medications By slowing down how your body normally breaks down medications in your gut and liver, grapefruit can increase the side effects of these drugs, increasing your risk for complications.
Ask your doctor or pharmacist if you can have fresh grapefruit or grapefruit juice while taking these and other medications. Grapefruit can be part of a healthy diet, but it can also interfere with certain medications. Ask your doctor before consuming grapefruit when taking medication. While this diet may help you drop pounds quickly, the weight will likely return as quickly as it left. Instead of focusing just on grapefruits, aim for the recommended 2 to 2.
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Citric acid, an organic acid found in grapefruit, may be effective at preventing them by binding with calcium in the kidneys and flushing it out of the body 41 , Also, citric acid has the ability to increase the volume and pH of your urine, producing an environment that is less favorable to the formation of kidney stones Grapefruit contains a lot of water and is, therefore, very hydrating.
While drinking lots of water is the best way to stay hydrated, eating water-rich foods can also help. Even if you live a busy, on-the-go lifestyle, you can still enjoy grapefruit on a regular basis without worrying about it taking up too much of your time.
For some people, consuming grapefruit and its juice may lead to medication interactions This is because it contains substances that inhibit cytochrome P, an enzyme your body uses to metabolize certain medications.
If you eat grapefruit while taking these medications, your body may not be able to break them down, which could cause an overdose and other adverse effects The medications most likely to interact with grapefruit include 44 :. If you are taking any of these medications, talk with your doctor before adding grapefruit to your diet. Citric acid, which is found in citrus fruits , is a common cause of enamel erosion, especially if you consume it in excess If you have particularly sensitive teeth, you may need to avoid acidic fruits.
However, there are some things you can do to preserve your tooth enamel while still enjoying grapefruit:. If you take certain medications or have sensitive teeth, you may need to limit your grapefruit intake or avoid it altogether.
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Consumption of grapefruit is associated with higher nutrient intakes and diet quality among adults, and more favorable anthropometrics in women, NHANES Food Nutr Res.
Department of Agriculture. Grapefruit, raw, pink and red, all areas. Updated April Effect of sequence of fruit intake in a meal on Satiety. Negative calorie foods: An empirical examination of what is fact or fiction. Department of Health and Human Services and U.
Published December The effects of grapefruit on weight and insulin resistance: Relationship to the metabolic syndrome. J Med Food. Joshi S, Mohan V. Indian J Med Res. Food and Drug Administration. July The effect of grapefruits Citrus paradisi on body weight and cardiovascular risk factors: A systematic review and meta-analysis of randomized clinical trials. Crit Rev Food Sci Nutr. Changes in intake of fruits and vegetables and weight change in United States men and women followed for up to 24 years: Analysis from three prospective cohort studies.
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I Accept Show Purposes. Table of Contents View All. Table of Contents. What Can You Eat? Pros and Cons. What Experts Say "While grapefruits are good for you, the health and fat-burning promises of the grapefruit diet are not evidence-based. If you are taking any medications, check with your doctor before adding grapefruit to your diet. Pros Grapefruit is nutritious. Cons Very restrictive Based on false assumptions. Grapefruit Nutrition Facts and Health Benefits.
Was this page helpful? Thanks for your feedback! Sign Up. What are your concerns? Verywell Fit uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles.
Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. On average, participants who ate half a grapefruit with each meal lost 3. However, many patients in the study lost more than 10 pounds.
The researchers speculate that the chemical properties of grapefruit reduce insulin levels and encourage weight loss.
The importance of this link lies with the hormone's weight management function.
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